Assay of Pungent Compounds

PID	Structure	Name	IC50	EC50	Assay Organism	Target Name	Assay_References	Note
PID00111		Butyl Isothiocyanate	305800 nM	-	Homo sapiens	T47D	Bioorg. Med. Chem. Lett., (2011) 21:15:4572	Antiproliferative activity against human T47D cells after 72 hrs by SRB assay
PID00111		Butyl Isothiocyanate	296000 nM	-	Homo sapiens	LoVo	Bioorg. Med. Chem. Lett., (2016) 26:2:667	Antiproliferative activity against human LoVo cells assessed as reduction in cell viability after 72 hrs by SRB assay
PID00111		Butyl Isothiocyanate	389800 nM	-	Homo sapiens	MCF7	Bioorg. Med. Chem. Lett., (2011) 21:15:4572	Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay
PID00111		Butyl Isothiocyanate	324200 nM	-	Homo sapiens	LoVo	Bioorg. Med. Chem. Lett., (2011) 21:15:4572	Antiproliferative activity against human LoVo cells after 72 hrs by SRB assay
PID00111		Butyl Isothiocyanate	413800 nM	-	Homo sapiens	A549	Bioorg. Med. Chem. Lett., (2011) 21:15:4572	Antiproliferative activity against human A549 cells after 72 hrs by SRB assay
PID00111		Butyl Isothiocyanate	-	403000 nM	Sclerotinia sclerotiorum	Sclerotinia sclerotiorum	Pest Manag Sci, (2011) 67:7:869	Fungistatic activity in Sclerotinia sclerotiorum assessed as sclerotial viability measured at 20 degC after 5 days
PID00111		Butyl Isothiocyanate	-	932000 nM	Sclerotinia sclerotiorum	Sclerotinia sclerotiorum	Pest Manag Sci, (2011) 67:7:869	Fungistatic activity in Sclerotinia sclerotiorum assessed as inhibition of mycelial growth in contact phase measured at 20 degC after 5 days
PID00111		Butyl Isothiocyanate	-	87300 nM	Sclerotinia sclerotiorum	Sclerotinia sclerotiorum	Pest Manag Sci, (2011) 67:7:869	Fungistatic activity in Sclerotinia sclerotiorum assessed as inhibition of mycelial growth in volatile phase measured at 20 degC after 5 days
PID00111		Butyl Isothiocyanate	-	42.83 ug.mL-1	Pectobacterium carotovorum	Pectobacterium carotovorum	CHEMBL3044893	Antibacterial activity against Pectobacterium carotovorum after 12 hr by turbidometric analysis
PID00111		Butyl Isothiocyanate	-	26.15 ug.mL-2	Rhizoctonia solani	Rhizoctonia solani	CHEMBL3044893	Antifungal activity against Rhizoctonia solani after 24 to 28 min by growth rate method