2D Structure
3D Structure
| Properties | |
|---|---|
| PID | PID00053 |
| Mol. Weight | 280.452 g/mol |
| LogP | 7.05 |
| Water solubility | In water, 1.59 mg/L at 25 °C |
| Hydrogen Bond Donor | 1 |
| Hydrogen Bond Acceptor | 2 |
| Rotatable Bonds | 14 |
| XLogP3 | 6.8 |
| Identifiers | |
|---|---|
| Formula | C18H32O2 |
| PubChem CID | 5280450 |
| FEMA | 3380 |
| Flavor Profile | Dairy |
| Smiles | CCCCC/C=C\C/C=C\CCCCCCCC(=O)O |
| InChl Key | OYHQOLUKZRVURQ-HZJYTTRNSA-N |
| InChl | InChI=1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9- |
| CAS Registry Number | 60-33-3, 2197-37-7, 506-21-8, 80969-37-5, 8024-22-4 |
| IUPAC Systematic Name | (9Z,12Z)-octadeca-9,12-dienoic acid |
Organ Location Map/System Distribution of Pungent Flavor Compounds’ Targets
Note: Known Targets (Gene) from 6952 literatures, DrugBank (http://www.drugbank.ca/), STITCH (http://stitch.embl.de/), ChEMBL (https://www.ebi.ac.uk/chembl/), Therapeutic Target Database (http://bidd.nus.edu.sg/group/ttd/), and Comparative Toxicogenomics Database (CTD, http://ctdbase.org/)
| English Name | Pinyin Name (Chinese Name) | Latin Name | Properties in TCM | merdians | View Graph |
|---|---|---|---|---|---|
| Artemisia argyi | Ai Ye(艾叶) | Argy Wormwood Leaf Equivalent plant: Artemisia mon | Warm,Pungent,Bitter | Lung,Spleen,Liver | View Graph |
| Croton tiglium | Ba Dou(巴豆) | Pu rging Croton | Hot,Pungent | Large Intestine, Stomach | View Graph |
| Medicinal Indianmulberry | Ba Ji Tian(巴戟天) | Morindae Officinalis Radix | Warm, Pungent, Sweet | Lung, Bladder, Heart | View Graph |
| Rhizoma Typhonii | Bai Fu Zi(白附子) | rhizome of Giant Typhonium | Warm,Pungent,Sweet | Spleen,Liver,Heart | View Graph |
| Dahurian Angelica | Bai Zhi(白芷) | Angelicae Dahuricae Radix | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Mylabris phalerata, Mylabris cichorii | Ban Mao(斑蝥) | Blister Beetle | Warm,Pungent | Spleen, Stomach, Kidney, Lung | View Graph |
| Ternate Pinellia | Ban Xia(半夏) | Pinellia ternata | Warm,Pungent | Spleen, Stomach, Kidney, Lung | View Graph |
| Wild Mint | Bo He (薄荷) | Menthae Haplocalycis Herba | Cool, Pungent | Liver, Lung | View Graph |
| Piper cubeba | Bi Cheng Qie(荜澄茄) | Cubeba Pepper | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Ricinus communis | Bi Ma Zi(蓖麻子) | Castorbean Seed | Mild,Pungent,Sweet | Lung,Stomach,Heart | View Graph |
| Betenutpalm | Bing Lang (槟榔) | Arecae Semen | Warm, Bitter, Pungent | Large Intestine, Stomach | View Graph |
| Fructus Xanthii sibirici | Cang Er Zi(苍耳子) | fruit of Siberian Cockleblur | Warm,Pungent,Bitter | Lung,Spleen,Liver | View Graph |
| Tsaoko | Cao Guo (草果) | Tsaoko Fructus | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Chinese Thorowax Equivalent plant: Bupleurum scorz | Chai Hu(柴胡) | Bupleuri Radix | Minor cold, Pungent, Bitter | Liver, Gallbladder, Lung | View Graph |
| Aquilaria agallocha | Chen Xiang(沉香) | Eaglewood Equivalent plant: Aquilaria sinensis | Warm,Pungent,Bitter | Lung,Spleen,Liver | View Graph |
| Chuanxiong (Wallich Ligusticum) Equivalent plant | Chuan Xiong (川芎) | Ligusticum chuanxiong Hort | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Eucommia ulmoides | Du Zhong Ye(杜仲叶) | Eucommia Leaf | Warm,Pungent | Spleen, Stomach, Kidney, Lung | View Graph |
| Centipeda minima | E Bu Shi Cao(鹅不食草) | Small Centipeda | Warm,Pungent | Spleen, Stomach, Kidney, Lung | View Graph |
| Divaricate Saposhnikovia | Fang Feng (防风) | Saposhnikoviae Radix | Warm, Pungent, Sweet | Lung, Bladder, Heart | View Graph |
| Fleshfingered Citron | Fo Shou (佛手) | Citri Sarcodactylis Fructus | Warm, Pungent, Sour, Bitter | Lung, Spleen, Stomach, Liver, Kidney | View Graph |
| Aconitum carmichaeli | Fu Zi(附子) | Prepared Common Monkshood Daughter Root Equivalent | Extreme Hot,Pungent,Sweet | Spleen,Heart,Kidney | View Graph |
| Chinese Nardostachys Equivalent plant: Nardostachy | Gan Song(甘松) | Nardostachyos Radix Et Rhizoma | Warm, Pungent, Sweet | Lung, Bladder, Heart | View Graph |
| Common Ginger Dried Rhizome | Gan Jiang (干姜) | Zingiberis Rhizoma | Hot, Pungent | Lung, Spleen, Stomach, Heart, Kidney | View Graph |
| Chinese Ligusticum Equivalent plant: Ligusticum je | Gao Ben (藁本) | Ligustici Rhizoma Et Radix | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Cassiabarktree Twig | Gui Zhi (桂枝) | Cinnamomi Ramulus | Warm, Pungent, Sweet | Lung, Bladder, Heart | View Graph |
| Fructus Carpesii | He Shi(鹤虱) | Common Carpesium Fruit | Bitter, pungent, neutral | Spleen,stomach | View Graph |
| Safflower | Hong Hua (红花) | Carthami Flos | Warm,Pungent | Spleen, Stomach, Kidney, Lung | View Graph |
| bark of Officinal magnolia | Hou Pu(厚朴) | Magnoliae Officinalis Cortex | Warm, Pungent, Bitter | Spleen, Liver | View Graph |
| Brassica juncea | Jie Zi(芥子) | India Mustard Seed | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Tuber Onion Seed | Jiu Cai Zi (韭菜子) | Allii Tuberosi Semen | Warm, Sweet, Pungent | Liver, Kidney | View Graph |
| Bush Redpepper | La Jiao (辣椒) | Capsici Fructus | Hot, Pungent | Lung, Spleen, Stomach, Heart, Kidney | View Graph |
| Garden Radish Seed | Lai Fu Zi(莱菔子) | Raphani Semen | Neural, Pungent, | Lung, Spleen, Stomach | View Graph |
| Rhizoma Ahemones Daddeanae | Liang Tou Jian(两头尖) | Radde Anemone Rhizome | Hot,Pungent | Large Intestine, Stomach | View Graph |
| Chinese Ephedra Equivalent plant: Ephedra equiseti | Ma Huang (麻黄) | Ephedrae Herba | Warm, Pungent, Slightly Bitter | Lung, Bladder | View Graph |
| Threeleaf Chastetree Fruit Equivalent plant: Vitex | Man Jing Zi (蔓荆子) | Viticis Fructus | Minor cold, Pungent, Bitter | Liver, Gallbladder, Lung | View Graph |
| Catclaw Buttercup Root | Mao Zhua Cao (猫爪草) | Ranunculi Ternati Radix | Warm, Pungent, Sweet | Lung, Bladder, Heart | View Graph |
| Common Aucklandia (Costustoot) | Mu Xiang(木香) | Aucklandiae Radix | Warm, Bitter, Pungent | Spleen, Large Intestine, Stomach, Gallbladder, Three End | View Graph |
| Daucus carota | Nan He Shi(南鹤虱) | Wild Carrot Fruit | Neural, Bitter, Pungent | Lung | View Graph |
| Great Burdock Fruit | Niu Bang Zi(牛蒡子) | Arctii Fructus | Cold, Bitter, Pungent | Bladder, Spleen, Liver，Stomach | View Graph |
| Euphorbia lathyris | Qian Jin Zi(千金子) | Caper Euphorbia Seed | Warm,Pungent | Spleen, Stomach, Kidney, Lung | View Graph |
| Cassiabarktree | Rou Gui (肉桂) | Cinnamomi Cortex | Hot, Sweet, Pungent | Liver, Heart, Spleen, Kidney | View Graph |
| Villous Amomum Equivalent plant: Amomum xanthioide | Sha Ren (砂仁) | Amomi Fructus | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Cnidium monnieri | She Chuang Zi(蛇床子) | Common Cnidium | Warm,Pungent,Bitter | Lung,Spleen,Liver | View Graph |
| Bugbane Equivalent plant: Cimicifuga dahurica, Ci | Sheng Ma(升麻) | Cimicifugae Rhizoma | Cold, Sweet, Pungent | Lung, Spleen, Large Intestine, Stomach | View Graph |
| Fresh Common Ginger | Sheng Jiang (生姜) | Zingiber Rhizoma Recens | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Oriental Sweetgum Resin | Su He Xiang (苏合香) | Styrax | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Arisaema consanguineum | Tian Nan Xing(天南星) | Reddish Jackinthepulpit Equivalent plant: Pinelli | Warm,Pungent,Bitter | Lung,Spleen,Liver | View Graph |
| Semen Hyoscyami | Tian Xian Zi(天仙子) | Henbane Seed | Warm,Pungent,Bitter | Lung,Spleen,Liver | View Graph |
| Lepidium apetalum [Syn. Lepidium micranthum ] | Ting Li Zi(葶苈子) | Pepperweed Seed Equivalent plant: Descurainia sop | Extreme Cold,Pungent,Bitter | Lung,Bladder | View Graph |
| Combined Spicebush | Wu Yao(乌药) | Linderae Radix | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Cacumen Tamaricis | Xi He Liu(西河柳) | Chinese Tamarisk Twig | Mild,Pungent,Sweet | Lung,Stomach,Heart | View Graph |
| Common Selfheal | Xia Ku Cao(夏枯草) | Prunellae Spica | Cold, Pungent, Bitter | Liver, Heart, Lung | View Graph |
| Periploca sepium | Xiang Jia Pi(香加皮) | Chinese Silkvine Root-bark | Minor Warm,Pungent,Bitter | Liver,Heart,Kidney | View Graph |
| Haichow Elsholtzia | Xiang Ru (香薷) | Moslae Herba | Minor Warm,Pungent | Lung, Spleen, Stomach | View Graph |
| Fennel Fruit | Xiao Hui Xiang (小茴香) | Foeniculi Fructus | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Allium macrostemon | Xie Bai(薤白) | Longstamen Onion Equivalent plant: Allium chinense | Warm,Pungent,Bitter | Lung,Spleen,Liver | View Graph |
| Paniculate Swallowwort | Xu Chang Qing(徐长卿) | Cynanchi Paniculati Radix Et Rhizoma | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Corydalis yanhusuo [Syn. Corydalis turtschaninov | Yan Hu Suo(延胡索) | Yanhusuo | Warm,Pungent,Bitter | Lung,Spleen,Liver | View Graph |
| Aromatic Turmeric | Yu Jin (郁金) | Curcumae Radix | Cold, Pungent, Bitter | Liver, Heart, Lung | View Graph |
| Daphne genkwa | Yuan Hua(芫花) | Lilac Daphne | Warm,Pungent,Bitter | Lung,Spleen,Liver | View Graph |
| Seville Orange Young Fruit Equivalent plant: Citru | Zhi Shi(枳实) | Aurantii Fructus Immaturus | Cold, Sour, Bitter, Pungent | Spleen, Stomach | View Graph |
| Perilia Fruit | Zi Su Zi (紫苏子) | Perillae Fructus | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Clove Tree | Ding Xiang (丁香) | Caryophylli Flos | Warm,Pungent | Spleen, Stomach, Kidney, Lung | View Graph |
| Chinese Clematis | Wei Ling Xian (威灵仙) | Clematidis Radix Et Rhizoma | Warm, Pungent, Salty | Bladder | View Graph |
| Corydalis yanhusuo [Syn. Corydalis turtschaninov | Yan Hu Suo(延胡索) | Yanhusuo | Warm,Pungent,Bitter | Lung,Spleen,Liver | View Graph |
| Euphorbia lathyris | Qian Jin Zi(千金子) | Caper Euphorbia Seed | Warm,Pungent | Spleen, Stomach, Kidney, Lung | View Graph |
| Croton tiglium | Ba Dou(巴豆) | Pu rging Croton | Hot,Pungent | Large Intestine, Stomach | View Graph |
| Ternate Pinellia | Ban Xia(半夏) | Pinellia ternata | Warm,Pungent | Spleen, Stomach, Kidney, Lung | View Graph |
| Ricinus communis | Bi Ma Zi(蓖麻子) | Castorbean Seed | Mild,Pungent,Sweet | Lung,Stomach,Heart | View Graph |
| Artemisia argyi | Ai Ye(艾叶) | Argy Wormwood Leaf Equivalent plant: Artemisia mon | Warm,Pungent,Bitter | Lung,Spleen,Liver | View Graph |
| Fructus Xanthii sibirici | Cang Er Zi(苍耳子) | fruit of Siberian Cockleblur | Warm,Pungent,Bitter | Lung,Spleen,Liver | View Graph |
| Semen Hyoscyami | Tian Xian Zi(天仙子) | Henbane Seed | Warm,Pungent,Bitter | Lung,Spleen,Liver | View Graph |
Linoleic acid is the main dietary form of n-6 essential fatty acids (EFA)and its lipid metabolites are known to mediate several infammatory pathways
in asthma. Linoleic acid (LA) (C18:2) has 18 carbon atoms in its chain, presenting with two C=C bonds, and is a member of a well-known series of n-6
PUFAs that is a precursor for arachidonic acid. Linoleic acid,
a poly-unsaturated fatty acid, is the major content of the sesame oil. Linoleic acid is now universally recognized to be an essential nutrient.
Linoleic acid present in rice and pulse may be readily available.
Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown
roles in the brain.
linoleicacid(LA) playacriticalroleinthegrowthand development of in fants and young children.
Linoleic acid (LA) is known to activate G-protein coupled receptors and connexin hemichannels (Cx HCs).
Linoleic acid (LA) is the most abundant PUFA in mammals.The effect of linoleic acid (LA) on health is still controversial. LA is one of the two essential fatty
acids, which means dietary supplementation of LA is necessary for maintaining cell activity. LA might enhance the incidence of some types of cancers via
stimulation of epithelial cell proliferation.
Linoleic acid (LA) is the major fatty acid in occidental diets. It is an essential omega-6 polyunsaturated fatty acid (PUFA), which is able to be
converted to arachidonic acid(AA).
Linoleic acid is the most abundant fatty acid present in plasma, and oxidation products of linoleic acid have been demonstrated to be highly stable
in biological samples, making them suitable markers for studying lipid peroxidation.
Linoleic acid (LA) is an important dietary fatty acid and a major component in many HF diets or the lipids that have been used to induce apoA-IV production.
Note: Click anywhere in the blank, you can drag the whole dynamic diagram. Click on a node, you can drag his location to see it more clearly. The blue circle represents pharmacology, toxicology, or daily use. Orange hexagon represents the pungent compounds.
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