2D Structure
3D Structure
| Properties | |
|---|---|
| PID | PID00091 |
| Mol. Weight | 136.238 g/mol |
| LogP | 2.17 |
| Water solubility | 0.00363 mol/L at 20 °C |
| Hydrogen Bond Donor | 0 |
| Hydrogen Bond Acceptor | 0 |
| Rotatable Bonds | 1 |
| XLogP3-AA | 2.8 |
| Identifiers | |
|---|---|
| Formula | C10H16 |
| PubChem CID | 7462 |
| FEMA | 3558 |
| Flavor Profile | Lemon |
| Smiles | CC1=CC=C(CC1)C(C)C |
| InChl Key | YHQGMYUVUMAZJR-UHFFFAOYSA-N |
| InChl | InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,6,8H,5,7H2,1-3H3 |
| CAS Registry Number | 99-86-5 |
| IUPAC Systematic Name | 1-methyl-4-propan-2-ylcyclohexa-1,3-diene |
Organ Location Map/System Distribution of Pungent Flavor Compounds’ Targets
Note: Known Targets (Gene) from 6952 literatures, DrugBank (http://www.drugbank.ca/), STITCH (http://stitch.embl.de/), ChEMBL (https://www.ebi.ac.uk/chembl/), Therapeutic Target Database (http://bidd.nus.edu.sg/group/ttd/), and Comparative Toxicogenomics Database (CTD, http://ctdbase.org/)
| English Name | Pinyin Name (Chinese Name) | Latin Name | Properties in TCM | merdians | View Graph |
|---|---|---|---|---|---|
| Radix Aconiti Kusnezoffii | Cao Wu(草乌) | Kusnezoff Monkshood Root | Hot,Pungent | Large Intestine, Stomach | View Graph |
| Artemisia argyi | Ai Ye(艾叶) | Argy Wormwood Leaf Equivalent plant: Artemisia mon | Warm,Pungent,Bitter | Lung,Spleen,Liver | View Graph |
| Chinese Star Anise | Ba Jiao Hui Xiang (八角茴香) | Anisi Stellati Fructus | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Wild Mint | Bo He (薄荷) | Menthae Haplocalycis Herba | Cool, Pungent | Liver, Lung | View Graph |
| Chuanxiong (Wallich Ligusticum) Equivalent plant | Chuan Xiong (川芎) | Ligusticum chuanxiong Hort | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Zedoray Rhizome | E Zhu (莪术) | Curcumae Rhizoma | Warm, Pungent, Bitter | Spleen, Liver | View Graph |
| Common Ginger Dried Rhizome | Gan Jiang (干姜) | Zingiberis Rhizoma | Hot, Pungent | Lung, Spleen, Stomach, Heart, Kidney | View Graph |
| Chinese Ligusticum Equivalent plant: Ligusticum je | Gao Ben (藁本) | Ligustici Rhizoma Et Radix | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Cassiabarktree Twig | Gui Zhi (桂枝) | Cinnamomi Ramulus | Warm, Pungent, Sweet | Lung, Bladder, Heart | View Graph |
| bark of Officinal magnolia | Hou Pu(厚朴) | Magnoliae Officinalis Cortex | Warm, Pungent, Bitter | Spleen, Liver | View Graph |
| Black Pepper | Hu Jiao (胡椒) | Piperis Fructus | Hot,Pungent | Large Intestine, Stomach | View Graph |
| Bunge Pricklyash Equivalent plant: Zanthoxylum sch | Hua Jiao (花椒) | Zanthoxyli Pericarpium | Warm,Pungent | Spleen, Stomach, Kidney, Lung | View Graph |
| Dahurian Rhododendron | Man Shan Hong (满山红) | Rhododendri Daurici Folium | Cold, Pungent, Bitter | Liver, Heart, Lung | View Graph |
| Threeleaf Chastetree Fruit Equivalent plant: Vitex | Man Jing Zi (蔓荆子) | Viticis Fructus | Minor cold, Pungent, Bitter | Liver, Gallbladder, Lung | View Graph |
| Folium Viticis Negundo | Mu Jing Ye(牡荆叶) | Hempleaf Negundo Chastetree Leaf | Neural, Bitter, Pungent | Lung | View Graph |
| Daucus carota | Nan He Shi(南鹤虱) | Wild Carrot Fruit | Neural, Bitter, Pungent | Lung | View Graph |
| Incised Notopterygium Equivalent plant: Notoptery | Qiang Huo(羌活) | Notopterygii Rhizoma Et Radix | Warm, Bitter, Pungent | Spleen, Large Intestine, Stomach, Gallbladder, Three End | View Graph |
| Green Tangerine Peel | Qing Pi (青皮) | Citri Reticulatae Pericarpium Viride | Warm, Pungent, Bitter | Spleen, Liver | View Graph |
| Cassiabarktree | Rou Gui (肉桂) | Cinnamomi Cortex | Hot, Sweet, Pungent | Liver, Heart, Spleen, Kidney | View Graph |
| Villous Amomum Equivalent plant: Amomum xanthioide | Sha Ren (砂仁) | Amomi Fructus | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Common Japanese Clubmoss Equivalent plant: Lycopod | Shen Jin Cao(伸筋草) | Lycopodii Herba | Warm, Bitter, Pungent | Large Intestine, Stomach | View Graph |
| Fresh Common Ginger | Sheng Jiang (生姜) | Zingiber Rhizoma Recens | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Evodia rutaecarpa | Wu Zhu Yu(吴茱萸) | Medicinal Evodia Equivalent plant: Evodia rutaecar | Pungent, bitter, hot | Liver, spleen,stomach | View Graph |
| Siebold Wildginger Equivalent plant: Asarum hetero | Xi Xin (细辛) | Asari Radix Et Rhizoma | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Haichow Elsholtzia | Xiang Ru (香薷) | Moslae Herba | Minor Warm,Pungent | Lung, Spleen, Stomach | View Graph |
| Lily Magnolia Buds Equivalent plant: Magnolia lili | Xin Yi (辛夷) | Magnoliae Flos | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Aromatic Turmeric | Yu Jin (郁金) | Curcumae Radix | Cold, Pungent, Bitter | Liver, Heart, Lung | View Graph |
| Illicium difengpi | Di Feng Pi(地枫皮) | Difengpi Anisetree Equivalent plant: Illicium maju | Warm,Slightly Pungent,Punkery | Bladder,Kidney | View Graph |
| Oriental Sweetgum Resin | Su He Xiang (苏合香) | Styrax | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
A l p h a - T e r p i n e n e i s a n i m p o r t a n t n a t u r a l f l a v o u r i n g c o m p o u n d p r e s e n t i n v a r i o u s f o o d s s u c h a s o r a n g e s , l i m e , o r e g a n o , a n d c o r i a n d e r a n d i s m a i n l y u s e d t o c o n f e r
p l e a s a n t o d o r t o i n d u s t r i a l f l u i d s .
T h e A l p h a - t e r p i n e n e s h o w e d f a s t e r t r y p a n o c i d a l e f f e c t c o m p a r e d t o c h e m o t h e r a p y . A l p h a - t e r p i n e n e w a s a b l e t o e x t e n d a n i m a l l o n g e v i t y , b u t s h o w e d n o c u r a t i v e e f c a c y .
A l p h a - t e r p i n e n e f r o m M . a l t e r n i f o l i a i s t h e o n e r e s p o n s i b l e f o r t h e t r y p a n o c i d a l e f f e c t . A l p h a - t e r p i n e n e a s s o c i a t e d w i t h D . A . c a n b e u s e d a s a n a l t e r n a t i v e
t r e a t m e n t f o r T . e v a n s i i n f e c t i o n . A l p h a - t e r p i n e n e , h a v e n o d i r e c t a n t i b a c t e r i a l a c t i v i t y a g a i n s t t h e S . a u r e u s 1 1 9 9 B s t r a i n a n d S . a u r e u s 1 1 9 9 w i l d . t h e
A l p h a - T e r p i n e n e t e s t s d i d n o t s h o w a c t i v i t y , b e i n g i n e f f i c i e n t b o t h i n t h e d i r e c t a c t i o n a s w e l l a s i n t h e p o t e n t i a t i n g a c t i o n a g a i n s t a n t i b a c t e r i a l s .
A l p h a - T e r p i n e n e c a u s e d e m b r y o a n d f o e t a l o x i c i t y w h e n g i v e n t o r a t s ( b y s t o m a c h t u b e ) a t d o s e s o f 6 0 m g / k g b o d y w e i g h t / d a y a n d a b o v e o n d a y s 6 - 1 5 o f p r e g n a n c y .
C h e m o t h e r a p y a s s o c i a t e w i t h A l p h a - t e r p i n e n e s h o w e d a c u r a t i v e e f c a c y o f 5 7 . 1 4 % . T h e M I C o f t h e e s s e n t i a l o i l a n d A l p h a - T e r p i n e n e p r e s e n t e d a v a l u e e" 1 0 2 4 g / m L .
Note: Click anywhere in the blank, you can drag the whole dynamic diagram. Click on a node, you can drag his location to see it more clearly. The blue circle represents pharmacology, toxicology, or daily use. Orange hexagon represents the pungent compounds.
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