| Name | Length | Bottleneck | Hydropathy | Charge | Polarity | Mutability |
|---|
| Ion channel |
| Name | Description |
|---|
| There are no data to be displayed... | |
| Gene | Trpv5 | |
| PDB ID | 6DMW | |
| Protein Name | ||
| Calmodulin-bound full-length rbTRPV5 | ||
| Organism | ||
| Oryctolagus cuniculus | ||
| Receptor Name | Transient receptor potential cation channel subfamily V member 5 | |
| UniProt ID | Q9XSM3 | |
| Function | ||
| Constitutively active calcium selective cation channel thought to be involved in Ca2+ reabsorption in kidney and intestine (PubMed:10085067, PubMed:11035011, PubMed:12574114, PubMed:29323279). Required for normal Ca2+ reabsorption in the kidney distal convoluted tubules (By similarity). The channel is activated by low internal calcium level and the current exhibits an inward rectification (PubMed:29323279). A Ca2+-dependent feedback regulation includes fast channel inactivation and slow current decay (PubMed:11035011). Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (PubMed:12574114) | ||
| Activity regulation | ||
| Activated by WNK3. | ||
| PID | Structure | Name | Source pungent TCM | FEMA or pubchemCID | Reference | ||
|---|---|---|---|---|---|---|---|
| No Result | |||||||