Transient receptor potential cation channel family information
Name Length Bottleneck Hydropathy Charge Polarity Mutability
Ion channel
Name Description
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Gene Trpc6
PDB ID 6CV9
Protein Name
Cytoplasmic domain of mTRPC6
Organism
Mus musculus
Receptor Name Short transient receptor potential channel 6
UniProt ID Q61143
Function
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.
Activity regulation
No data available

Ligand List of this Receptor

PID Structure Name Source pungent TCM FEMA or pubchemCID Reference
No Result