Name | Length | Bottleneck | Hydropathy | Charge | Polarity | Mutability |
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Ion channel |
Name | Description |
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There are no data to be displayed... | |
Gene | Trpc4 | |
PDB ID | 5Z96 | |
Protein Name | ||
Structure of the mouse TRPC4 ion channel | ||
Organism | ||
Mus musculus | ||
Receptor Name | Short transient receptor potential channel 4 | |
UniProt ID | Q9QUQ5 | |
Function | ||
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion. Trpc4 deficient mice lack a store-operated calcium entry in endothelial cells. | ||
Activity regulation | ||
No data available | ||
PID | Structure | Name | Source pungent TCM | FEMA or pubchemCID | Reference | ||
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No Result |