Transient receptor potential cation channel family information
Name Length Bottleneck Hydropathy Charge Polarity Mutability
Ion channel
Name Description
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Gene Trpc4
PDB ID 5Z96
Protein Name
Structure of the mouse TRPC4 ion channel
Organism
Mus musculus
Receptor Name Short transient receptor potential channel 4
UniProt ID Q9QUQ5
Function
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion. Trpc4 deficient mice lack a store-operated calcium entry in endothelial cells.
Activity regulation
No data available

Ligand List of this Receptor

PID Structure Name Source pungent TCM FEMA or pubchemCID Reference
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