| Name | Length | Bottleneck | Hydropathy | Charge | Polarity | Mutability |
|---|
| Ion channel |
| Name | Description |
|---|
| There are no data to be displayed... | |
| Gene | TRPC6 | |
| PDB ID | 5YX9 | |
| Protein Name | ||
| Cryo-EM structure of human TRPC6 at 3.8A resolution | ||
| Organism | ||
| Homo sapiens | ||
| Receptor Name | Short transient receptor potential channel 6 | |
| UniProt ID | Q9Y210 | |
| Function | ||
| Thought to form a receptor-activated non-selective calcium permeant cation channel (PubMed:19936226, PubMed:23291369). Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C (PubMed:26892346). Seems not to be activated by intracellular calcium store depletion. | ||
| Activity regulation | ||
| No data available | ||
| PID | Structure | Name | Source pungent TCM | FEMA or pubchemCID | Reference | ||
|---|---|---|---|---|---|---|---|
| No Result | |||||||