Name | Length | Bottleneck | Hydropathy | Charge | Polarity | Mutability |
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Ion channel |
Name | Description |
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There are no data to be displayed... | |
Gene | TRPC6 | |
PDB ID | 5YX9 | |
Protein Name | ||
Cryo-EM structure of human TRPC6 at 3.8A resolution | ||
Organism | ||
Homo sapiens | ||
Receptor Name | Short transient receptor potential channel 6 | |
UniProt ID | Q9Y210 | |
Function | ||
Thought to form a receptor-activated non-selective calcium permeant cation channel (PubMed:19936226, PubMed:23291369). Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C (PubMed:26892346). Seems not to be activated by intracellular calcium store depletion. | ||
Activity regulation | ||
No data available | ||
PID | Structure | Name | Source pungent TCM | FEMA or pubchemCID | Reference | ||
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No Result |