| Name | Length | Bottleneck | Hydropathy | Charge | Polarity | Mutability |
|---|
| Ion channel |
| Name | Description |
|---|
| There are no data to be displayed... | |
| Gene | TRPV5 | |
| PDB ID | 5OEO | |
| Protein Name | ||
| Solution structure of the complex of TRPV5(655-725) with a Calmodulin E32Q/E68Q double mutant | ||
| Organism | ||
| Homo sapiens | ||
| Receptor Name | Transient receptor potential cation channel subfamily V member 5 | |
| UniProt ID | Q9NQA5 | |
| Function | ||
| Constitutively active calcium selective cation channel thought to be involved in Ca2+ reabsorption in kidney and intestine (PubMed:11549322, PubMed:18768590). Required for normal Ca2+ reabsorption in the kidney distal convoluted tubules (By similarity). The channel is activated by low internal calcium level and the current exhibits an inward rectification (PubMed:11549322, PubMed:18768590). A Ca2+-dependent feedback regulation includes fast channel inactivation and slow current decay (By similarity). Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity) | ||
| Activity regulation | ||
| Activated by WNK3. | ||
| PID | Structure | Name | Source pungent TCM | FEMA or pubchemCID | Reference | ||
|---|---|---|---|---|---|---|---|
| No Result | |||||||