Transient receptor potential cation channel family information
Name Length Bottleneck Hydropathy Charge Polarity Mutability
Ion channel
Name Description
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Gene Trpv3
PDB ID 4N5Q
Protein Name
Crystal structure of the N-terminal ankyrin repeat domain of TRPV3
Organism
Mus musculus
Receptor Name Transient receptor potential cation channel subfamily V member 4
UniProt ID Q8K424
Function
Putative receptor-activated non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen) (By similarity).
Activity regulation
No data available

Ligand List of this Receptor

PID Structure Name Source pungent TCM FEMA or pubchemCID Reference
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