Name | Length | Bottleneck | Hydropathy | Charge | Polarity | Mutability |
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Ion channel |
Name | Description |
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There are no data to be displayed... | |
Gene | Trpv3 | |
PDB ID | 4N5Q | |
Protein Name | ||
Crystal structure of the N-terminal ankyrin repeat domain of TRPV3 | ||
Organism | ||
Mus musculus | ||
Receptor Name | Transient receptor potential cation channel subfamily V member 4 | |
UniProt ID | Q8K424 | |
Function | ||
Putative receptor-activated non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen) (By similarity). | ||
Activity regulation | ||
No data available | ||
PID | Structure | Name | Source pungent TCM | FEMA or pubchemCID | Reference | ||
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No Result |