2D Structure
3D Structure
Properties | |
---|---|
PID | PID00037 |
Mol. Weight | 59.112 g/mol |
LogP | 0.19 |
Water solubility | Solubility in water very good |
Hydrogen Bond Donor | 0 |
Hydrogen Bond Acceptor | 1 |
Rotatable Bonds | 0 |
XLogP3-AA | 0.3 |
Identifiers | |
---|---|
Formula | C3H9N |
PubChem CID | 1146 |
FEMA | 3241 |
Flavor Profile | Old Fish; Saline Taste;Pungent, Fishy, Ammoniacal, Fishy, Amine Odor, A Fish-Like Odor At Low Concentrations Changing To An Ammonia-Like Odor At Higher Concentrations. |
Smiles | CN(C)C |
InChl Key | GETQZCLCWQTVFV-UHFFFAOYSA-N |
InChl | InChI=1S/C3H9N/c1-4(2)3/h1-3H3 |
CAS Registry Number | 75-50-3 |
IUPAC Systematic Name | N,N-dimethylmethanamine |
Organ Location Map/System Distribution of Pungent Flavor Compounds’ Targets
Note: Known Targets (Gene) from 6952 literatures, DrugBank (http://www.drugbank.ca/), STITCH (http://stitch.embl.de/), ChEMBL (https://www.ebi.ac.uk/chembl/), Therapeutic Target Database (http://bidd.nus.edu.sg/group/ttd/), and Comparative Toxicogenomics Database (CTD, http://ctdbase.org/)
English Name | Pinyin Name (Chinese Name) | Latin Name | Properties in TCM | merdians | View Graph |
---|---|---|---|---|---|
Chuanxiong (Wallich Ligusticum) Equivalent plant | Chuan Xiong (川芎) | Ligusticum chuanxiong Hort | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
Siebold Wildginger Equivalent plant: Asarum hetero | Xi Xin (细辛) | Asari Radix Et Rhizoma | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
Trimethylamine (TMA, (CH3)3N) has attracted considerable research attention in recent years as an indicator for food freshness, in particular for fish, seafood, meat, wine, and milk
Trimethylamine (TMA) is a type of poisonous and harmfulgases in various fields, such as food and biotechnology indus-tries.
Trimethylamine (TMA) is an organic compound with the formula N(CH3)3. This colorless, hygroscopic, and flammable tertiary amine has a strong "fishy" odor in low concentrations and an ammonia-like odor at higher concentrations. It is a gas at room temperature but is usually sold in pressurized gas cylinders or as a 40% solution in water. TMA is a nitrogenous base and can be readily protonated to give trimethylammonium cation. Trimethylammonium chloride is a hygroscopic colorless solid prepared from hydrochloric acid. Trimethylamine is a good nucleophile, and this reaction is the basis of most of its applications.
Note: Click anywhere in the blank, you can drag the whole dynamic diagram. Click on a node, you can drag his location to see it more clearly. The blue circle represents pharmacology, toxicology, or daily use. Orange hexagon represents the pungent compounds.
1. Bota G M, Harrington P B. Direct detection of trimethylamine in meat food products using ion mobility spectrometry[J]. Talanta, 2006, 68(3): 629-635.
2. Yang, R., Huang, X., Wang, Z., Zhou, Y., & Liu, L. A chemisorption-based microcantilever chemical sensor for the detection of trimethylamine[J]. Sensors and actuators B: chemical, 2010, 145(1): 474-479.
3. Zhang, R., Wang, L., Deng, J., Zhou, T., Lou, Z., Zhang, T. Hierarchical structure with heterogeneous phase as high performance sensing materials for trimethylamine gas detecting[J]. Sensors and Actuators B: Chemical, 2015, 220: 1224-1231.
4. Baliño-Zuazo L, Barranco A. A novel liquid chromatography–mass spectrometric method for the simultaneous determination of trimethylamine, dimethylamine and methylamine in fishery products[J]. Food chemistry, 2016, 196: 1207-1214.
5. Tong M, Dai G, Gao D. WO3 thin film sensor prepared by sol–gel technique and its low-temperature sensing properties to trimethylamine[J]. Materials Chemistry and Physics, 2001, 69(1-3): 176-179.
6. El Barbri, N., Amari, A., Vinaixa, M., Bouchikhi, B., Correig, X., Llobet, E. Building of a metal oxide gas sensor-based electronic nose to assess the freshness of sardines under cold storage[J]. Sensors and Actuators B: Chemical, 2007, 128(1): 235-244.
7. Zhang W H, Zhang W D. Fabrication of SnO2–ZnO nanocomposite sensor for selective sensing of trimethylamine and the freshness of fishes[J]. Sensors and Actuators B: Chemical, 2008, 134(2): 403-408.
8. Chu, X., Han, Y., Zhou, S., Shui, H. Trimethylamine sensing properties of nano-SnO2 prepared using microwave heating method[J]. Ceramics International, 2010, 36(7): 2175-2180.
9. Cohen L J. Cutting choline conversion in commensals to treat cardiovascular disease[J]. Science Translational Medicine, 2018, 10(457): eaav0333.
10. https://en.wikipedia.org/wiki/Trimethylamine