2D Structure
3D Structure
| Properties | |
|---|---|
| PID | PID00126 |
| Mol. Weight | 154.253 g/mol |
| LogP | 3.05 |
| Water solubility | 0.0017 mol/L at 20 °C |
| Hydrogen Bond Donor | 0 |
| Hydrogen Bond Acceptor | 1 |
| Rotatable Bonds | 1 |
| XLogP3-AA | 2.7 |
| Identifiers | |
|---|---|
| Formula | C10H18O |
| PubChem CID | 26447 |
| FEMA | 2667 |
| Flavor Profile | Slight Peppermint Odor, Bitter; Green, Fresh, Mint |
| Smiles | CC(C)[C@@H]1CC[C@@H](C)CC1=O |
| InChl Key | NFLGAXVYCFJBMK-BDAKNGLRSA-N |
| InChl | InChI=1S/C10H18O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-9H,4-6H2,1-3H3/t8-,9+/m1/s1 |
| CAS Registry Number | 89-80-5, 14073-97-3 |
| IUPAC Systematic Name | (2S,5R)-5-methyl-2-propan-2-ylcyclohexan-1-one |
Organ Location Map/System Distribution of Pungent Flavor Compounds’ Targets
Note: Known Targets (Gene) from 6952 literatures, DrugBank (http://www.drugbank.ca/), STITCH (http://stitch.embl.de/), ChEMBL (https://www.ebi.ac.uk/chembl/), Therapeutic Target Database (http://bidd.nus.edu.sg/group/ttd/), and Comparative Toxicogenomics Database (CTD, http://ctdbase.org/)
| English Name | Pinyin Name (Chinese Name) | Latin Name | Properties in TCM | merdians | View Graph |
|---|---|---|---|---|---|
| Wild Mint | Bo He (薄荷) | Menthae Haplocalycis Herba | Cool, Pungent | Liver, Lung | View Graph |
| Chinese Thorowax Equivalent plant: Bupleurum scorz | Chai Hu(柴胡) | Bupleuri Radix | Minor cold, Pungent, Bitter | Liver, Gallbladder, Lung | View Graph |
| bark of Officinal magnolia | Hou Pu(厚朴) | Magnoliae Officinalis Cortex | Warm, Pungent, Bitter | Spleen, Liver | View Graph |
| Asiatic Pennywort | Ji Xue Cao (积雪草) | Centellae Herba | Cold, Sweet, Bitter | Liver, Spleen, Kidney | View Graph |
| Fineleaf Schizonepeta | Jing Jie (荆芥) | Schizonepetae Herba | Minor Warm, Pungent | Lung, Liver | View Graph |
| Herba Schizonepetae | Jing Jie Sui (荆芥穗) | Schizonepetae Spica | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Bush Redpepper | La Jiao (辣椒) | Capsici Fructus | Hot, Pungent | Lung, Spleen, Stomach, Heart, Kidney | View Graph |
| Chinese Ephedra Equivalent plant: Ephedra equiseti | Ma Huang (麻黄) | Ephedrae Herba | Warm, Pungent, Slightly Bitter | Lung, Bladder | View Graph |
| Bugbane Equivalent plant: Cimicifuga dahurica, Ci | Sheng Ma(升麻) | Cimicifugae Rhizoma | Cold, Sweet, Pungent | Lung, Spleen, Large Intestine, Stomach | View Graph |
| Fresh Common Ginger | Sheng Jiang (生姜) | Zingiber Rhizoma Recens | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Siebold Wildginger Equivalent plant: Asarum hetero | Xi Xin (细辛) | Asari Radix Et Rhizoma | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Paniculate Swallowwort | Xu Chang Qing(徐长卿) | Cynanchi Paniculati Radix Et Rhizoma | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Tokyo Violet | Zi Hua Di Ding (紫花地丁) | Peucedani Decursivi Radix | Cold, Pungent, Bitter | Liver, Heart, Lung | View Graph |
| Alpinia katsumadai | Cao Dou Kou(草豆蔻) | Katsumada Galangal | Warm,Pungent | Spleen, Stomach, Kidney, Lung | View Graph |
| Haichow Elsholtzia | Xiang Ru (香薷) | Moslae Herba | Minor Warm,Pungent | Lung, Spleen, Stomach | View Graph |
| Perilla frutescens var. arguta | Zi Su(紫苏叶) | Common Perilla Equivalent plant: Perilla frutescen | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
Menthone is a constituent of the essential oils of pennyroyal, peppermint, Mentha arvensis, Pelargonium geraniums, and others. In most essential oils, it is a minor compound. This is the cause for the fact that it was first synthesized by oxidation of menthol in 1881 before it was found in essential oils in 1891.
Note: Click anywhere in the blank, you can drag the whole dynamic diagram. Click on a node, you can drag his location to see it more clearly. The blue circle represents pharmacology, toxicology, or daily use. Orange hexagon represents the pungent compounds.
1.Bhatia K S, Singh J. Mechanism of transport enhancement of LHRH through porcine epidermis by terpenes and iontophoresis: permeability and lipid extraction studies[J]. Pharmaceutical research, 1998, 15(12): 1857-1862.
2.Dambolena J S, Lpez A G, Cnepa M C, et al. Inhibitory effect of cyclic terpenes (limonene, menthol, menthone and thymol) on Fusarium verticillioides MRC 826 growth and fumonisin B1 biosynthesis[J]. Toxicon, 2008, 51(1): 37-44.
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5.Hu G, Yuan X, Zhang S, et al. Research on choleretic effect of menthol, menthone, pluegone, isomenthone, and limonene in DanShu capsule[J]. International immunopharmacology, 2015, 24(2): 191-197.
6.https://en.wikipedia.org/wiki/Menthone