2D Structure
3D Structure
| Properties | |
|---|---|
| PID | PID00027 |
| Mol. Weight | 128.174 g/mol |
| LogP | 2.96 |
| Water solubility | In water, 31 mg/L at 25 °C |
| Hydrogen Bond Donor | 0 |
| Hydrogen Bond Acceptor | 0 |
| Rotatable Bonds | 0 |
| XLogP3 | 3.3 |
| Identifiers | |
|---|---|
| Formula | C10H8 |
| PubChem CID | 931 |
| FEMA | / |
| Flavor Profile | Aromatic Odor, Odor Of Mothballs, Characteritic Odor (Plates) |
| Smiles | c1ccc2ccccc2c1 |
| InChl Key | UFWIBTONFRDIAS-UHFFFAOYSA-N |
| InChl | InChI=1S/C10H8/c1-2-6-10-8-4-3-7-9(10)5-1/h1-8H |
| CAS Registry Number | 91-20-3 |
| IUPAC Systematic Name | naphthalene |
Organ Location Map/System Distribution of Pungent Flavor Compounds’ Targets
Note: Known Targets (Gene) from 6952 literatures, DrugBank (http://www.drugbank.ca/), STITCH (http://stitch.embl.de/), ChEMBL (https://www.ebi.ac.uk/chembl/), Therapeutic Target Database (http://bidd.nus.edu.sg/group/ttd/), and Comparative Toxicogenomics Database (CTD, http://ctdbase.org/)
| English Name | Pinyin Name (Chinese Name) | Latin Name | Properties in TCM | merdians | View Graph |
|---|---|---|---|---|---|
| Chinese Thorowax Equivalent plant: Bupleurum scorz | Chai Hu(柴胡) | Bupleuri Radix | Minor cold, Pungent, Bitter | Liver, Gallbladder, Lung | View Graph |
| Clove Tree | Ding Xiang (丁香) | Caryophylli Flos | Warm,Pungent | Spleen, Stomach, Kidney, Lung | View Graph |
| Divaricate Saposhnikovia | Fang Feng (防风) | Saposhnikoviae Radix | Warm, Pungent, Sweet | Lung, Bladder, Heart | View Graph |
| Cassiabarktree Twig | Gui Zhi (桂枝) | Cinnamomi Ramulus | Warm, Pungent, Sweet | Lung, Bladder, Heart | View Graph |
| Wild Buckwheat Rhizome | Jin Qiao Mai(金荞麦) | Fagopyri Dibotryis Rhizoma | Cool, Pungent, Astringent | Lung | View Graph |
| Chinese Ephedra Equivalent plant: Ephedra equiseti | Ma Huang (麻黄) | Ephedrae Herba | Warm, Pungent, Slightly Bitter | Lung, Bladder | View Graph |
| Dahurian Rhododendron | Man Shan Hong (满山红) | Rhododendri Daurici Folium | Cold, Pungent, Bitter | Liver, Heart, Lung | View Graph |
| Catclaw Buttercup Root | Mao Zhua Cao (猫爪草) | Ranunculi Ternati Radix | Warm, Pungent, Sweet | Lung, Bladder, Heart | View Graph |
| Common Japanese Clubmoss Equivalent plant: Lycopod | Shen Jin Cao(伸筋草) | Lycopodii Herba | Warm, Bitter, Pungent | Large Intestine, Stomach | View Graph |
| Siebold Wildginger Equivalent plant: Asarum hetero | Xi Xin (细辛) | Asari Radix Et Rhizoma | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Lily Magnolia Buds Equivalent plant: Magnolia lili | Xin Yi (辛夷) | Magnoliae Flos | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Pericarpium Arecae | Da Fu Pi(大腹皮) | pericarp of Betelnutpalm | Minor Warm,Pungent | Lung, Spleen, Stomach | View Graph |
| Chuanxiong (Wallich Ligusticum) Equivalent plant | Chuan Xiong (川芎) | Ligusticum chuanxiong Hort | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Dahurian Angelica | Bai Zhi(白芷) | Angelicae Dahuricae Radix | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Illicium difengpi | Di Feng Pi(地枫皮) | Difengpi Anisetree Equivalent plant: Illicium maju | Warm,Slightly Pungent,Punkery | Bladder,Kidney | View Graph |
| Chinese Angelica Equivalent plant: Phlojodicarpus | Dang Gui (当归) | Angelicae Sinensis Radix | Warm,Pungent,Sweet | Spleen,Liver,Heart | View Graph |
| Alpinia katsumadai | Cao Dou Kou(草豆蔻) | Katsumada Galangal | Warm,Pungent | Spleen, Stomach, Kidney, Lung | View Graph |
| Chinese Clematis | Wei Ling Xian (威灵仙) | Clematidis Radix Et Rhizoma | Warm, Pungent, Salty | Bladder | View Graph |
| Haichow Elsholtzia | Xiang Ru (香薷) | Moslae Herba | Minor Warm,Pungent | Lung, Spleen, Stomach | View Graph |
| Styrax benzoin | An Xi Xiang(安息香) | Sumatra Snowbell Equivalent plant: Styrax tonkinen | Mild,Pungent,Bitter | Spleen,Heart | View Graph |
Naphthalene is an organic compound with formula C10H8. It is the simplest polycyclic aromatic hydrocarbon. As an aromatic hydrocarbon, naphthalene's
structure consists of a fused pair of benzene rings. It is best known as the main ingredient of traditional mothballs. Naphthalene has been used as a
household fumigant. It is used in pyrotechnic special effects such as the generation of black smoke and simulated explosions.[citation needed] It is
used to create artificial pores in the manufacture of high-porosity grinding wheels. In the past, naphthalene was administered orally to kill parasitic
worms in livestock. Naphthalene and its alkyl homologs are the major constituents of creosote. Naphthalene is used in engineering to study heat transfer
using mass sublimation. However, Exposure to large amounts of naphthalene may cause confusion, nausea, vomiting, diarrhea, blood in the urine, and
jaundice (yellow coloration of the skin due to dysfunction of the liver).
Note: Click anywhere in the blank, you can drag the whole dynamic diagram. Click on a node, you can drag his location to see it more clearly. The blue circle represents pharmacology, toxicology, or daily use. Orange hexagon represents the pungent compounds.
1 Germansky M, Jamall I S. Organ-specific effects of naphthalene on tissue peroxidation, glutathione peroxidases and superoxide dismutase in the rat[J]. Archives of toxicology, 1988, 61(6): 480-483.
2 Germansky M, Jamall I S. Organ-specific effects of naphthalene on tissue peroxidation, glutathione peroxidases and superoxide dismutase in the rat[J]. Archives of toxicology, 1988, 61(6): 480-483.
3 Schmeltz I, Tosk J, Hoffmann D. Formation and determination of naphthalenes in cigarette smoke[J]. Analytical chemistry, 1976, 48(4): 645-650.
4 RAW Johnstone, PM Quan. Naphthalenes in Cigarette Smoke[J]. Nature, 1963 , 199 (4899) :1184
5 https://en.wikipedia.org/wiki/Naphthalene
6 https://medlineplus.gov/ency/article/002477.htm