2D Structure
3D Structure
| Properties | |
|---|---|
| PID | PID00021 |
| Mol. Weight | 152.237 g/mol |
| LogP | 1.52 |
| Water solubility | 0.011 mol/L at 20 °C |
| Hydrogen Bond Donor | 1 |
| Hydrogen Bond Acceptor | 1 |
| Rotatable Bonds | 1 |
| XLogP3-AA | 1.6 |
| Identifiers | |
|---|---|
| Formula | C10H16O |
| PubChem CID | 10582 |
| FEMA | 3439 |
| Flavor Profile | Mint, Cool |
| Smiles | CC1(C)C2CC=C(CO)C1C2 |
| InChl Key | RXBQNMWIQKOSCS-UHFFFAOYSA-N |
| InChl | InChI=1S/C10H16O/c1-10(2)8-4-3-7(6-11)9(10)5-8/h3,8-9,11H,4-6H2,1-2H3 |
| CAS Registry Number | 515-00-4 |
| IUPAC Systematic Name | (6,6-dimethyl-4-bicyclo[3.1.1]hept-3-enyl)methanol |
Organ Location Map/System Distribution of Pungent Flavor Compounds’ Targets
Note: Known Targets (Gene) from 6952 literatures, DrugBank (http://www.drugbank.ca/), STITCH (http://stitch.embl.de/), ChEMBL (https://www.ebi.ac.uk/chembl/), Therapeutic Target Database (http://bidd.nus.edu.sg/group/ttd/), and Comparative Toxicogenomics Database (CTD, http://ctdbase.org/)
| English Name | Pinyin Name (Chinese Name) | Latin Name | Properties in TCM | merdians | View Graph |
|---|---|---|---|---|---|
| Oriental Sweetgum Resin | Su He Xiang (苏合香) | Styrax | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Alpinia katsumadai | Cao Dou Kou(草豆蔻) | Katsumada Galangal | Warm,Pungent | Spleen, Stomach, Kidney, Lung | View Graph |
Myrtenol is a bio-active isolate of Taxus. Myrtenol, a monoterpene alcohol, has been shown to possess numerous pharmacological properties,
such as gastroprotective, antinociceptive, anticancer, antihyperglycemic, antihypertensive, anti-inflammatory, antioxidant, anti-apoptotic, and
anxiolytic-like effects
Note: Click anywhere in the blank, you can drag the whole dynamic diagram. Click on a node, you can drag his location to see it more clearly. The blue circle represents pharmacology, toxicology, or daily use. Orange hexagon represents the pungent compounds.
1 https://en.wikipedia.org/wiki/Myrtenol
2 Viana A F S C, da Silva F V, Fernandes H B, et al. Gastroprotective effect of (‐)‐myrtenol against ethanol‐induced acute gastric lesions: possible mechanisms[J]. Journal of Pharmacy and Pharmacology, 2016, 68(8): 1085-1092.
3 de Britto R M, da Silva-Neto J A, Mesquita T R R, et al. Myrtenol protects against myocardial ischemia-reperfusion injury through antioxidant and anti-apoptotic dependent mechanisms[J]. Food and Chemical Toxicology, 2018, 111: 557-566.
4 Evstatieva L, Todorova M, Antonova D, et al. Chemical composition of the essential oils of Rhodiola rosea L. of three different origins[J]. Pharmacognosy magazine, 2010, 6(24): 256.
5 Sepici-Dincel A, Açıkgöz Ş, Cevik C, et al. Effects of in vivo antioxidant enzyme activities of myrtle oil in normoglycaemic and alloxan diabetic rabbits[J]. Journal of ethnopharmacology, 2007, 110(3): 498-503.
6 Gomes B S, Neto B P S, Lopes E M, et al. Anti-inflammatory effect of the monoterpene myrtenol is dependent on the direct modulation of neutrophil migration and oxidative stress[J]. Chemico-biological interactions, 2017, 273: 73-81.
7 Moreira M R C, Salvadori M G S S, de Almeida A A C, et al. Anxiolytic-like effects and mechanism of (−)-myrtenol: A monoterpene alcohol[J]. Neuroscience letters, 2014, 579: 119-124.
8 R.O. Silva, M.S. Salvadori, F.B.M. Sousa, M.S. Santos, N.S. Carvalho, D.P. Sousa, B.S.Gomes, F.A. Oliveira, A.L.R. Barbosa, R.M. Freitas, R.N. Almeida, J.R. Medeiros,Evaluation of the anti-inflammatory and antinociceptive effects of myrtenol,a plant derived monoterpene alcohol, in mice, Flavour Fragrance J. 29 (2014)184–192.
9 van Brederode J, Atak S, Kessler A, et al. The terpenoids Myrtenol and Verbenol act on δ subunit-containing GABAA receptors and enhance tonic inhibition in dentate gyrus granule cells[J]. Neuroscience letters, 2016, 628: 91-97.