2D Structure
3D Structure
Properties | |
---|---|
PID | PID00152 |
Mol. Weight | 46.025 g/mol |
LogP | -0.27 |
Water solubility | 10.5 mol/L at 20 °C |
Hydrogen Bond Donor | 1 |
Hydrogen Bond Acceptor | 2 |
Rotatable Bonds | 0 |
XLogP3-AA | -0.2 |
Identifiers | |
---|---|
Formula | CH2O2 |
PubChem CID | 284 |
FEMA | 2487 |
Flavor Profile | Pungent, Penetrating Odor, Sour; Savory |
Smiles | O=CO |
InChl Key | BDAGIHXWWSANSR-UHFFFAOYSA-N |
InChl | InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3) |
CAS Registry Number | 64-18-6, 992-98-3, 147173-07-7 |
IUPAC Systematic Name | formic acid |
Organ Location Map/System Distribution of Pungent Flavor Compounds’ Targets
Note: Known Targets (Gene) from 6952 literatures, DrugBank (http://www.drugbank.ca/), STITCH (http://stitch.embl.de/), ChEMBL (https://www.ebi.ac.uk/chembl/), Therapeutic Target Database (http://bidd.nus.edu.sg/group/ttd/), and Comparative Toxicogenomics Database (CTD, http://ctdbase.org/)
English Name | Pinyin Name (Chinese Name) | Latin Name | Properties in TCM | merdians | View Graph |
---|---|---|---|---|---|
Scolopendra subspinipes mutilans | Wu Gong(蜈蚣) | Centipede | Warm,Pungent | Spleen, Stomach, Kidney, Lung | View Graph |
Formic acid, systematically named methanoic acid, is the simplest carboxylic acid. The chemical formula is HCOOH or HCO2H. It is an important intermediate
in chemical synthesis and occurs naturally, most notably in some ants.
Formic acid has been always regarded as a promising re- actant for the fuel cell technology.
Note: Click anywhere in the blank, you can drag the whole dynamic diagram. Click on a node, you can drag his location to see it more clearly. The blue circle represents pharmacology, toxicology, or daily use. Orange hexagon represents the pungent compounds.
1. https://en.wikipedia.org/wiki/Formic_acid
2. Kienhuis H, Blasse G, Matze J. Action of anhydrous formic acid on peptides and proteins[J]. Nature, 1959, 184(4704): 2015.
3. Goosen N J, De Wet L F, Görgens J F. Effects of formic acid in abalone diets that contain ingredients derived from fish processing by-products[J]. Aquaculture International, 2018, 26(3): 857-868.
4. Liu X, Li S, Liu Y, et al. Formic acid: A versatile renewable reagent for green and sustainable chemical synthesis[J]. Chinese Journal of Catalysis, 2015, 36(9): 1461-1475.
5. Sarkar P B. Decomposition of formic acid by periodate[J]. Nature, 1951, 168(4264): 122.
6. Adams D, Boopathy R. Use of formic acid to control vibriosis in shrimp aquaculture[J]. Biologia, 2013, 68(6): 1017-1021.
7. Liu, X., Li, S., Liu, Y., Cao, Y.. Formic acid: A versatile renewable reagent for green and sustainable chemical synthesis[J]. Chinese Journal of Catalysis, 2015, 36(9): 1461-1475.
8. Ray P C. Isomorphism and Chemical Constitution: Constitution of Formic Acid and Formates[J]. Nature, 1934, 133(3365): 646.
9. Piggott R A, Shreir L L. Micropitting of Titanium during Anodic Oxidation in Formic Acid[J]. Nature, 1961, 189(4760): 216.
10. Gasser, C. A., Čvančarová, M., Ammann, E. M., Schäffer, A., Shahgaldian, P., Corvini, P. F. X.. Sequential lignin depolymerization by combination of biocatalytic and formic acid/formate treatment steps[J]. Applied microbiology and biotechnology, 2017, 101(6): 2575-2588.
11. Harris L. The Absorption Spectrum of Formic Acid Vapour in Relation to Molecular Associations[J]. Nature, 1926, 118(2970): 482.
12. Herrero E, Feliu J M. Understanding formic acid oxidation mechanism on platinum single crystal electrodes[J]. Current Opinion in Electrochemistry, 2018.
13. Capon A, Parsons R. The oxidation of formic acid at noble metal electrodes Part III. Intermediates and mechanism on platinum electrodes[J]. Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 1973, 45(2): 205-231.
14. Clavilier, J., Parsons, R., Durand, R., Lamy, C., Leger, J. M. Formic acid oxidation on single crystal platinum electrodes. Comparison with polycrystalline platinum[J]. Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 1981, 124(1-2): 321-326.
15. Wolter O, Willsau J, Heitbaum J. Reaction pathways of the anodic oxidation of formic acid on Pt evidenced by 18O labeling—a DEMS study[J]. Journal of The Electrochemical Society, 1985, 132(7): 1635-1638.
16. Ferre-Vilaplana, A., Perales-Rondón, J. V., Busó-Rogero, C., Feliu, J. M., Herrero, E. Formic acid oxidation on platinum electrodes: a detailed mechanism supported by experiments and calculations on well-defined surfaces[J]. Journal of Materials Chemistry A, 2017, 5(41): 21773-21784.
17. Cuesta, A., Cabello, G., Gutiérrez, C., Osawa, M. Adsorbed formate: the key intermediate in the oxidation of formic acid on platinum electrodes[J]. Physical Chemistry Chemical Physics, 2011, 13(45): 20091-20095.