2D Structure
3D Structure
| Properties | |
|---|---|
| PID | PID00072 |
| Mol. Weight | 204.357 g/mol |
| LogP | 4.52 |
| Water solubility | less than 1 mg/mL at 70° F (NTP, 1992) |
| Hydrogen Bond Donor | 0 |
| Hydrogen Bond Acceptor | 0 |
| Rotatable Bonds | 0 |
| XLogP3 | 4.4 |
| Identifiers | |
|---|---|
| Formula | C15H24 |
| PubChem CID | 5281515 |
| FEMA | 2252 |
| Flavor Profile | Fried, Spice, Wood |
| Smiles | C=C1CCC=C(C)CC[C@@H]2[C@@H]1CC2(C)C |
| InChl Key | NPNUFJAVOOONJE-GFUGXAQUSA-N |
| InChl | InChI=1S/C15H24/c1-11-6-5-7-12(2)13-10-15(3,4)14(13)9-8-11/h6,13-14H,2,5,7-10H2,1,3-4H3/b11-6+/t13-,14-/m1/s1 |
| CAS Registry Number | 87-44-5 |
| IUPAC Systematic Name | (1R,4E,9S)-4,11,11-trimethyl-8-methylidenebicyclo[7.2.0]undec-4-ene |
Organ Location Map/System Distribution of Pungent Flavor Compounds’ Targets
Note: Known Targets (Gene) from 6952 literatures, DrugBank (http://www.drugbank.ca/), STITCH (http://stitch.embl.de/), ChEMBL (https://www.ebi.ac.uk/chembl/), Therapeutic Target Database (http://bidd.nus.edu.sg/group/ttd/), and Comparative Toxicogenomics Database (CTD, http://ctdbase.org/)
| English Name | Pinyin Name (Chinese Name) | Latin Name | Properties in TCM | merdians | View Graph |
|---|---|---|---|---|---|
| Dryobalanops aromatica | Bing Pian(冰片) | Borneol | Minor cold,Pungent,Bitter | Lung,Spleen,Heart | View Graph |
| Fructus Xanthii sibirici | Cang Er Zi(苍耳子) | fruit of Siberian Cockleblur | Warm,Pungent,Bitter | Lung,Spleen,Liver | View Graph |
| Chinese Thorowax Equivalent plant: Bupleurum scorz | Chai Hu(柴胡) | Bupleuri Radix | Minor cold, Pungent, Bitter | Liver, Gallbladder, Lung | View Graph |
| Motherwort Fruit | Chong Wei Zi(茺蔚子) | Leonuri Fructus | Cold, Bitter, Pungent | Bladder, Spleen, Liver，Stomach | View Graph |
| Zedoray Rhizome | E Zhu (莪术) | Curcumae Rhizoma | Warm, Pungent, Bitter | Spleen, Liver | View Graph |
| Chinese Ligusticum Equivalent plant: Ligusticum je | Gao Ben (藁本) | Ligustici Rhizoma Et Radix | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Safflower | Hong Hua (红花) | Carthami Flos | Warm,Pungent | Spleen, Stomach, Kidney, Lung | View Graph |
| Bunge Pricklyash Equivalent plant: Zanthoxylum sch | Hua Jiao (花椒) | Zanthoxyli Pericarpium | Warm,Pungent | Spleen, Stomach, Kidney, Lung | View Graph |
| Common Turmeric Equivalent plant: Curcuma aromati | Jiang Huang (姜黄) | Curcumae Longae Rhizoma | Warm, Pungent, Bitter | Spleen, Liver | View Graph |
| Fineleaf Schizonepeta | Jing Jie (荆芥) | Schizonepetae Herba | Minor Warm, Pungent | Lung, Liver | View Graph |
| Frankincense, Olibanum | Ru Xiang (乳香) | Olibanum | Warm，Bitter, Pungent | Spleen, Lung | View Graph |
| Wilson Citron | Xiang Yuan(香橼) | Citri Fructus | Warm, Pungent, Sour, Slightly Bitter | Lung, Spleen, Liver | View Graph |
| Leonurus heterophyllus [Syn. Leonurus artemisia] | Yi Mu Cao(益母草) | Wormwood-like Motherwort Equivalent plant: Leonuru | Minor cold,Pungent,Bitter | Lung,Spleen,Heart | View Graph |
| Virgate Wormwood Herb | Yin Chen(茵陈) | Artemisiae Scopariae Herba | Cold, Bitter, pungent | Bladder, Spleen, Liver, Stomach | View Graph |
| Apple Mint | Yu Xian Cao(鱼腥草) | Houttuyniae Herba | Cold, Pungent | Lung | View Graph |
| Perilia Fruit | Zi Su Zi (紫苏子) | Perillae Fructus | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Cablin Potchouli | Guang Huo Xiang (广藿香) | Pogostemonis Herba | Minor Warm,Pungent | Lung, Spleen, Stomach | View Graph |
| Fresh Common Ginger | Sheng Jiang (生姜) | Zingiber Rhizoma Recens | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Chinese Angelica Equivalent plant: Phlojodicarpus | Dang Gui (当归) | Angelicae Sinensis Radix | Warm,Pungent,Sweet | Spleen,Liver,Heart | View Graph |
| Oriental Sweetgum Resin | Su He Xiang (苏合香) | Styrax | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Lily Magnolia Buds Equivalent plant: Magnolia lili | Xin Yi (辛夷) | Magnoliae Flos | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Perilla frutescens var. arguta | Zi Su(紫苏叶) | Common Perilla Equivalent plant: Perilla frutescen | Warm, Pungent | Lung, Spleen, Stomach | View Graph |
| Murraya paniculata [Syn. Chalcas paniculata] | Jiu Li Xiang(九里香) | Common Jasminorange Equivalent plant: Murraya pan | Neural, Bitter, Pungent | Lung | View Graph |
| Dryobalanops aromatica | Bing Pian(冰片) | Borneol | Minor cold,Pungent,Bitter | Lung,Spleen,Heart | View Graph |
| Fructus Xanthii sibirici | Cang Er Zi(苍耳子) | fruit of Siberian Cockleblur | Warm,Pungent,Bitter | Lung,Spleen,Liver | View Graph |
Caryophyllene or (-)--caryophyllene, is a natural bicyclic sesquiterpene that is a constituent of many essential oils, especially clove oil, the oil from the stems and flowers of Syzygium aromaticum (cloves), the essential oil of Cannabis sativa, rosemary, and hops.
-Caryophyllene (BCP) is an important cannabinoid originated from the essential oils of different species, such as Cinnamomum spp., Piper nigrum and Cannabis sativa. As a natural bicyclic sesquiterpene, BCP has been reported to serve as a full agonist of cannabinoid receptor type 2 (CB2R) by a selective binding. -Caryophyllene (BCP), an important cannabinoid derived from the essential oils of different species, has displayed pharmacological properties in different kinds of tissues and cells. -Caryophyllene is a major volatile compound found in large quantities in the essential oil of Cannabis sativa L. (up to 35%)
Beta-Caryophyllene 1 is a sesquiterpene present in natural products e.g. the oil of cloves, cinnamon leaves and copaiba balsam, all of which have been used as natural remedies and as fragrances. The odour of b-caryophyllene, is described as woody and spicy. Beta-caryophyllene is an unsaturated hydrocarbon it can be expected to autoxidize when air exposed. -Caryophyllene is a sesquiterpene which is commonly used as fragrance chemical because of its pleasant odour.
-caryophyllene is a major component from the essential oil of Alpinia purpurata. betacaryophyllene (-caryophyllene) is a natural sesquiterpene present in many plant essential oils, such as Achyrocline satureioides, being a major component of some traditional medicinal herbs. Also in this case, -caryophyllene is one of the major chemical components of this essential oil.
Beta-Caryophyllene (BCP) is a sesquiterpene that binds to the cannabinoid 2 (CB2) receptor and exerts anti-inflammatory effects. b-Caryophyllene (BCP) is a natural sesquiterpene found in essential oils from a variety of plant species, including medicinal plants (e.g., cinnamon, origanum, black pepper, and marijuana).
-Caryophyllene (b-Car) is a natural antioxidant. It is Cannabis-derived cannabinoid receptors type 2 (CB2R) agonist.
Note: Click anywhere in the blank, you can drag the whole dynamic diagram. Click on a node, you can drag his location to see it more clearly. The blue circle represents pharmacology, toxicology, or daily use. Orange hexagon represents the pungent compounds.
1. https://en.wikipedia.org/wiki/Caryophyllene
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